Nakano T, Doi T, Yoshimoto J, Doya K. (2010). A kinetic model of dopamine- and calcium-dependent striatal synaptic plasticity. PLoS computational biology. 6 [PubMed]

See more from authors: Nakano T · Doi T · Yoshimoto J · Doya K

References and models cited by this paper

Ahmed SH. (2004). Neuroscience. Addiction as compulsive reward prediction. Science (New York, N.Y.). 306 [PubMed]

Akopian G, Musleh W, Smith R, Walsh JP. (2000). Functional state of corticostriatal synapses determines their expression of short- and long-term plasticity. Synapse (New York, N.Y.). 38 [PubMed]

Arbuthnott GW, Ingham CA, Wickens JR. (2000). Dopamine and synaptic plasticity in the neostriatum. Journal of anatomy. 196 ( Pt 4) [PubMed]

Balleine BW, Doya K, O'Doherty J, Sakagami M. (2007). Current trends in decision making. Annals of the New York Academy of Sciences. 1104 [PubMed]

Banke TG et al. (2000). Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Barbano PE et al. (2007). A mathematical tool for exploring the dynamics of biological networks. Proceedings of the National Academy of Sciences of the United States of America. 104 [PubMed]

Bernard V, Somogyi P, Bolam JP. (1997). Cellular, subcellular, and subsynaptic distribution of AMPA-type glutamate receptor subunits in the neostriatum of the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]

Bezprozvanny I, Watras J, Ehrlich BE. (1991). Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature. 351 [PubMed]

Bhalla US, Iyengar R. (1999). Emergent properties of networks of biological signaling pathways. Science (New York, N.Y.). 283 [PubMed]

Bibb JA. (2003). Role of Cdk5 in neuronal signaling, plasticity, and drug abuse. Neuro-Signals. 12 [PubMed]

Bibb JA et al. (1999). Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature. 402 [PubMed]

Bito H, Takemoto-Kimura S. (2003). Ca(2+)/CREB/CBP-dependent gene regulation: a shared mechanism critical in long-term synaptic plasticity and neuronal survival. Cell calcium. 34 [PubMed]

Bonsi P, Pisani A, Bernardi G, Calabresi P. (2003). Stimulus frequency, calcium levels and striatal synaptic plasticity. Neuroreport. 14 [PubMed]

Bradshaw JM, Kubota Y, Meyer T, Schulman H. (2003). An ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling. Proceedings of the National Academy of Sciences of the United States of America. 100 [PubMed]

Calabresi P, Centonze D, Gubellini P, Marfia GA, Bernardi G. (1999). Glutamate-triggered events inducing corticostriatal long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Calabresi P, Giacomini P, Centonze D, Bernardi G. (2000). Levodopa-induced dyskinesia: a pathological form of striatal synaptic plasticity? Annals of neurology. 47 [PubMed]

Calabresi P et al. (2000). Dopamine and cAMP-regulated phosphoprotein 32 kDa controls both striatal long-term depression and long-term potentiation, opposing forms of synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Calabresi P, Maj R, Pisani A, Mercuri NB, Bernardi G. (1992). Long-term synaptic depression in the striatum: physiological and pharmacological characterization. The Journal of neuroscience : the official journal of the Society for Neuroscience. 12 [PubMed]

Calabresi P, Pisani A, Mercuri NB, Bernardi G. (1992). Long-term Potentiation in the Striatum is Unmasked by Removing the Voltage-dependent Magnesium Block of NMDA Receptor Channels. The European journal of neuroscience. 4 [PubMed]

Calabresi P et al. (2001). Activation of metabotropic glutamate receptor subtype 1/protein kinase C/mitogen-activated protein kinase pathway is required for postischemic long-term potentiation in the striatum. Molecular pharmacology. 60 [PubMed]

Carter AG, Sabatini BL. (2004). State-dependent calcium signaling in dendritic spines of striatal medium spiny neurons. Neuron. 44 [PubMed]

Castellani GC, Bazzani A, Cooper LN. (2009). Toward a microscopic model of bidirectional synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 106 [PubMed]

Castellani GC, Quinlan EM, Bersani F, Cooper LN, Shouval HZ. (2005). A model of bidirectional synaptic plasticity: from signaling network to channel conductance. Learning & memory (Cold Spring Harbor, N.Y.). 12 [PubMed]

Centonze D et al. (2003). Receptor subtypes involved in the presynaptic and postsynaptic actions of dopamine on striatal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

Charpier S, Deniau JM. (1997). In vivo activity-dependent plasticity at cortico-striatal connections: evidence for physiological long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America. 94 [PubMed]

Charpier S, Mahon S, Deniau JM. (1999). In vivo induction of striatal long-term potentiation by low-frequency stimulation of the cerebral cortex. Neuroscience. 91 [PubMed]

Choi S, Lovinger DM. (1997). Decreased probability of neurotransmitter release underlies striatal long-term depression and postnatal development of corticostriatal synapses. Proceedings of the National Academy of Sciences of the United States of America. 94 [PubMed]

Cooper DM. (2003). Molecular and cellular requirements for the regulation of adenylate cyclases by calcium. Biochemical Society transactions. 31 [PubMed]

D'Alcantara P, Schiffmann SN, Swillens S. (2003). Bidirectional synaptic plasticity as a consequence of interdependent Ca2+-controlled phosphorylation and dephosphorylation pathways. The European journal of neuroscience. 17 [PubMed]

Day M, Wokosin D, Plotkin JL, Tian X, Surmeier DJ. (2008). Differential excitability and modulation of striatal medium spiny neuron dendrites. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]

Deng YP et al. (2007). Differential localization of the GluR1 and GluR2 subunits of the AMPA-type glutamate receptor among striatal neuron types in rats. Journal of chemical neuroanatomy. 33 [PubMed]

Derkach V, Barria A, Soderling TR. (1999). Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 96 [PubMed]

Desdouits F, Cohen D, Nairn AC, Greengard P, Girault JA. (1995). Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase I in vitro and in vivo. The Journal of biological chemistry. 270 [PubMed]

Desdouits F, Siciliano JC, Greengard P, Girault JA. (1995). Dopamine- and cAMP-regulated phosphoprotein DARPP-32: phosphorylation of Ser-137 by casein kinase I inhibits dephosphorylation of Thr-34 by calcineurin. Proceedings of the National Academy of Sciences of the United States of America. 92 [PubMed]

Doya K. (2007). Reinforcement learning: Computational theory and biological mechanisms. HFSP journal. 1 [PubMed]

Doya K, Wickens J, Yoshimoto J, Nakano T. (2009). Calcium responses model in striatum dependent on timed input sources International Conference of Artificial Neurai Networks 2009 (ICANN 2009). I

Ehlers MD. (2000). Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting. Neuron. 28 [PubMed]

Esteban JA et al. (2003). PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. Nature neuroscience. 6 [PubMed]

Fernandez E, Schiappa R, Girault JA, Le Novère N. (2006). DARPP-32 is a robust integrator of dopamine and glutamate signals. PLoS computational biology. 2 [PubMed]

Gerfen CR. (2000). Molecular effects of dopamine on striatal-projection pathways. Trends in neurosciences. 23 [PubMed]

Gerfen CR et al. (1990). D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science (New York, N.Y.). 250 [PubMed]

Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P. (1989). Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II. The Journal of biological chemistry. 264 [PubMed]

Gonon F et al. (2000). Geometry and kinetics of dopaminergic transmission in the rat striatum and in mice lacking the dopamine transporter. Progress in brain research. 125 [PubMed]

Gould TD, Manji HK. (2005). DARPP-32: A molecular switch at the nexus of reward pathway plasticity. Proceedings of the National Academy of Sciences of the United States of America. 102 [PubMed]

Grace AA. (2000). Gating of information flow within the limbic system and the pathophysiology of schizophrenia. Brain research. Brain research reviews. 31 [PubMed]

Greengard P. (2001). The neurobiology of dopamine signaling. Bioscience reports. 21 [PubMed]

Greengard P, Allen PB, Nairn AC. (1999). Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade. Neuron. 23 [PubMed]

Greengard P, Nairn AC, Girault JA, Desdouits F, Siciliano JC. (1998). Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons. Biochem J. 330 ( Pt 1)

Greengard P et al. (1998). The DARPP-32/protein phosphatase-1 cascade: a model for signal integration. Brain research. Brain research reviews. 26 [PubMed]

Guillou JL, Nakata H, Cooper DM. (1999). Inhibition by calcium of mammalian adenylyl cyclases. The Journal of biological chemistry. 274 [PubMed]

Halpain S, Girault JA, Greengard P. (1990). Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices. Nature. 343 [PubMed]

Hamada M et al. (2005). Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons. The Journal of pharmacology and experimental therapeutics. 315 [PubMed]

Hayer A, Bhalla US. (2005). Molecular switches at the synapse emerge from receptor and kinase traffic. PLoS computational biology. 1 [PubMed]

Hemmings HC, Greengard P, Tung HY, Cohen P. (1984). DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1. Nature. 310 [PubMed]

Hemmings HC, Nairn AC, Greengard P. (1984). DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1. The Journal of biological chemistry. 259 [PubMed]

Hemmings HC, Williams KR, Konigsberg WH, Greengard P. (1984). DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine. The Journal of biological chemistry. 259 [PubMed]

Hempel CM, Vincent P, Adams SR, Tsien RY, Selverston AI. (1996). Spatio-temporal dynamics of cyclic AMP signals in an intact neural circuitm. Nature. 384 [PubMed]

Hersch SM et al. (1995). Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents. The Journal of neuroscience : the official journal of the Society for Neuroscience. 15 [PubMed]

Hikosaka O, Nakamura K, Nakahara H. (2006). Basal ganglia orient eyes to reward. Journal of neurophysiology. 95 [PubMed]

Hoops S et al. (2006). COPASI--a COmplex PAthway SImulator. Bioinformatics (Oxford, England). 22 [PubMed]

Hu SC, Chrivia J, Ghosh A. (1999). Regulation of CBP-mediated transcription by neuronal calcium signaling. Neuron. 22 [PubMed]

Hudmon A, Schulman H. (2002). Neuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function. Annual review of biochemistry. 71 [PubMed]

Hudmon A, Schulman H. (2002). Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II. The Biochemical journal. 364 [PubMed]

Håkansson K, Lindskog M, Pozzi L, Usiello A, Fisone G. (2004). DARPP-32 and modulation of cAMP signaling: involvement in motor control and levodopa-induced dyskinesia. Parkinsonism & related disorders. 10 [PubMed]

Janssens V et al. (2003). Identification and functional analysis of two Ca2+-binding EF-hand motifs in the B"/PR72 subunit of protein phosphatase 2A. The Journal of biological chemistry. 278 [PubMed]

Kawaguchi Y. (1997). Neostriatal cell subtypes and their functional roles. Neuroscience research. 27 [PubMed]

Kelley AE. (2004). Memory and addiction: shared neural circuitry and molecular mechanisms. Neuron. 44 [PubMed]

King MM et al. (1984). Mammalian brain phosphoproteins as substrates for calcineurin. The Journal of biological chemistry. 259 [PubMed]

Klee CB, Draetta GF, Hubbard MJ. (1988). Calcineurin. Advances in enzymology and related areas of molecular biology. 61 [PubMed]

Kötter R. (1994). Postsynaptic integration of glutamatergic and dopaminergic signals in the striatum. Progress in neurobiology. 44 [PubMed]

Kötter R, Wickens J. (1995). Interactions of glutamate and dopamine in a computational model of the striatum. Journal of computational neuroscience. 2 [PubMed]

Lee HK, Barbarosie M, Kameyama K, Bear MF, Huganir RL. (2000). Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature. 405 [PubMed]

Lengyel I et al. (2004). Autonomous activity of CaMKII is only transiently increased following the induction of long-term potentiation in the rat hippocampus. The European journal of neuroscience. 20 [PubMed]

Li T, Chalifour LE, Paudel HK. (2007). Phosphorylation of protein phosphatase 1 by cyclin-dependent protein kinase 5 during nerve growth factor-induced PC12 cell differentiation. The Journal of biological chemistry. 282 [PubMed]

Lindskog M, Kim M, Wikström MA, Blackwell KT, Kotaleski JH. (2006). Transient calcium and dopamine increase PKA activity and DARPP-32 phosphorylation. PLoS computational biology. 2 [PubMed]

Lisman J, Schulman H, Cline H. (2002). The molecular basis of CaMKII function in synaptic and behavioural memory. Nature reviews. Neuroscience. 3 [PubMed]

Liu F et al. (2001). Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 98 [PubMed]

Liu F, Virshup DM, Nairn AC, Greengard P. (2002). Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors. The Journal of biological chemistry. 277 [PubMed]

Malinow R, Malenka RC. (2002). AMPA receptor trafficking and synaptic plasticity. Annual review of neuroscience. 25 [PubMed]

Markevich NI, Hoek JB, Kholodenko BN. (2004). Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades. The Journal of cell biology. 164 [PubMed]

Mons N, Cooper DM. (1994). Selective expression of one Ca(2+)-inhibitable adenylyl cyclase in dopaminergically innervated rat brain regions. Brain research. Molecular brain research. 22 [PubMed]

Nairn AC et al. (2004). The role of DARPP-32 in the actions of drugs of abuse. Neuropharmacology. 47 Suppl 1 [PubMed]

Nestler EJ. (2001). Molecular basis of long-term plasticity underlying addiction. Nature reviews. Neuroscience. 2 [PubMed]

Nishi A et al. (2002). Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A. Journal of neurochemistry. 81 [PubMed]

Nishi A et al. (2000). Amplification of dopaminergic signaling by a positive feedback loop. Proceedings of the National Academy of Sciences of the United States of America. 97 [PubMed]

Nishi A, Snyder GL, Greengard P. (1997). Bidirectional regulation of DARPP-32 phosphorylation by dopamine. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]

Nishi A, Snyder GL, Nairn AC, Greengard P. (1999). Role of calcineurin and protein phosphatase-2A in the regulation of DARPP-32 dephosphorylation in neostriatal neurons. Journal of neurochemistry. 72 [PubMed]

Nishi A et al. (2005). Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades. Proceedings of the National Academy of Sciences of the United States of America. 102 [PubMed]

Passafaro M, Piëch V, Sheng M. (2001). Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons. Nature neuroscience. 4 [PubMed]

Paul S et al. (2000). The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Rakhilin SV et al. (2004). A network of control mediated by regulator of calcium/calmodulin-dependent signaling. Science (New York, N.Y.). 306 [PubMed]

Reynolds JN, Hyland BI, Wickens JR. (2001). A cellular mechanism of reward-related learning. Nature. 413 [PubMed]

Reynolds JN, Wickens JR. (2000). Substantia nigra dopamine regulates synaptic plasticity and membrane potential fluctuations in the rat neostriatum, in vivo. Neuroscience. 99 [PubMed]

Reynolds JN, Wickens JR. (2002). Dopamine-dependent plasticity of corticostriatal synapses. Neural networks : the official journal of the International Neural Network Society. 15 [PubMed]

Roche KW, O'Brien RJ, Mammen AL, Bernhardt J, Huganir RL. (1996). Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit. Neuron. 16 [PubMed]

Schultz W, Dayan P, Montague PR. (1997). A neural substrate of prediction and reward. Science (New York, N.Y.). 275 [PubMed]

Sivakumaran S, Hariharaputran S, Mishra J, Bhalla US. (2003). The Database of Quantitative Cellular Signaling: management and analysis of chemical kinetic models of signaling networks. Bioinformatics (Oxford, England). 19 [PubMed]

Snyder GL et al. (2000). Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Snyder GL et al. (2003). Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists. Neuropharmacology. 45 [PubMed]

Spencer JP, Murphy KP. (2000). Bi-directional changes in synaptic plasticity induced at corticostriatal synapses in vitro. Experimental brain research. 135 [PubMed]

Svenningsson P, Nairn AC, Greengard P. (2005). DARPP-32 mediates the actions of multiple drugs of abuse. The AAPS journal. 7 [PubMed]

Svenningsson P et al. (2004). DARPP-32: an integrator of neurotransmission. Annual review of pharmacology and toxicology. 44 [PubMed]

Swanson GT, Kamboj SK, Cull-Candy SG. (1997). Single-channel properties of recombinant AMPA receptors depend on RNA editing, splice variation, and subunit composition. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]

Tan CH, He X, Yang J, Ong WY. (2006). Changes in AMPA subunit expression in the mouse brain after chronic treatment with the antidepressant maprotiline: a link between noradrenergic and glutamatergic function? Experimental brain research. 170 [PubMed]

Usui H et al. (1998). Activation of protein phosphatase 2A by cAMP-dependent protein kinase-catalyzed phosphorylation of the 74-kDa B'' (delta) regulatory subunit in vitro and identification of the phosphorylation sites. FEBS letters. 430 [PubMed]

Wickens JR, Begg AJ, Arbuthnott GW. (1996). Dopamine reverses the depression of rat corticostriatal synapses which normally follows high-frequency stimulation of cortex in vitro. Neuroscience. 70 [PubMed]

Wilson CJ, Kawaguchi Y. (1996). The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]

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Kato A, Morita K. (2016). Forgetting in Reinforcement Learning Links Sustained Dopamine Signals to Motivation. PLoS computational biology. 12 [PubMed]

Kim B, Hawes SL, Gillani F, Wallace LJ, Blackwell KT. (2013). Signaling pathways involved in striatal synaptic plasticity are sensitive to temporal pattern and exhibit spatial specificity. PLoS computational biology. 9 [PubMed]

Manninen T, Hituri K, Kotaleski JH, Blackwell KT, Linne ML. (2010). Postsynaptic signal transduction models for long-term potentiation and depression. Frontiers in computational neuroscience. 4 [PubMed]

Nakano T, Yoshimoto J, Doya K. (2013). A model-based prediction of the calcium responses in the striatal synaptic spines depending on the timing of cortical and dopaminergic inputs and post-synaptic spikes. Frontiers in computational neuroscience. 7 [PubMed]

Oliveira RF, Kim M, Blackwell KT. (2012). Subcellular location of PKA controls striatal plasticity: stochastic simulations in spiny dendrites. PLoS computational biology. 8 [PubMed]

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