Zheng Y et al. (2019). Deep Sequencing of Somatosensory Neurons Reveals Molecular Determinants of Intrinsic Physiological Properties Neuron.

See more from authors: Zheng Y · Liu P · Bai L · Trimmer JS · Bean BP · Ginty DD

References and models cited by this paper

Bocksteins E, Snyders DJ. (2012). Electrically silent Kv subunits: their molecular and functional characteristics. Physiology (Bethesda, Md.). 27 [PubMed]

Carter BC, Bean BP. (2009). Sodium entry during action potentials of mammalian neurons: incomplete inactivation and reduced metabolic efficiency in fast-spiking neurons. Neuron. 64 [PubMed]

Carter BC, Bean BP. (2011). Incomplete inactivation and rapid recovery of voltage-dependent sodium channels during high-frequency firing in cerebellar Purkinje neurons. Journal of neurophysiology. 105 [PubMed]

Chang W et al. (2016). Merkel disc is a serotonergic synapse in the epidermis for transmitting tactile signals in mammals. Proceedings of the National Academy of Sciences of the United States of America. 113 [PubMed]

Chawla K, Tripathi S, Thommesen L, Lægreid A, Kuiper M. (2013). TFcheckpoint: a curated compendium of specific DNA-binding RNA polymerase II transcription factors. Bioinformatics (Oxford, England). 29 [PubMed]

Chi XX, Nicol GD. (2007). Manipulation of the potassium channel Kv1.1 and its effect on neuronal excitability in rat sensory neurons. Journal of neurophysiology. 98 [PubMed]

Chiu IM et al. (2014). Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity. eLife. 3 [PubMed]

Coetzee WA et al. (1999). Molecular diversity of K+ channels. Annals of the New York Academy of Sciences. 868 [PubMed]

Delmas P, Hao J, Rodat-Despoix L. (2011). Molecular mechanisms of mechanotransduction in mammalian sensory neurons. Nature reviews. Neuroscience. 12 [PubMed]

Dib-Hajj SD, Cummins TR, Black JA, Waxman SG. (2010). Sodium channels in normal and pathological pain. Annual review of neuroscience. 33 [PubMed]

Du X, Gamper N. (2013). Potassium channels in peripheral pain pathways: expression, function and therapeutic potential. Current neuropharmacology. 11 [PubMed]

Du X et al. (2014). Control of somatic membrane potential in nociceptive neurons and its implications for peripheral nociceptive transmission. Pain. 155 [PubMed]

Dubin AE, Patapoutian A. (2010). Nociceptors: the sensors of the pain pathway. The Journal of clinical investigation. 120 [PubMed]

Everill B, Rizzo MA, Kocsis JD. (1998). Morphologically identified cutaneous afferent DRG neurons express three different potassium currents in varying proportions. Journal of neurophysiology. 79 [PubMed]

Fleming MS, Luo W. (2013). The anatomy, function, and development of mammalian Aß low-threshold mechanoreceptors. Frontiers in biology. 8 [PubMed]

François A et al. (2015). The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function. Cell reports. 10 [PubMed]

Földy C et al. (2016). Single-cell RNAseq reveals cell adhesion molecule profiles in electrophysiologically defined neurons. Proceedings of the National Academy of Sciences of the United States of America. 113 [PubMed]

Gemes G et al. (2013). Failure of action potential propagation in sensory neurons: mechanisms and loss of afferent filtering in C-type units after painful nerve injury. The Journal of physiology. 591 [PubMed]

Glazebrook PA et al. (2002). Potassium channels Kv1.1, Kv1.2 and Kv1.6 influence excitability of rat visceral sensory neurons. The Journal of physiology. 541 [PubMed]

Gold MS, Shuster MJ, Levine JD. (1996). Characterization of six voltage-gated K+ currents in adult rat sensory neurons. Journal of neurophysiology. 75 [PubMed]

Gorokhova S et al. (2014). Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor. PLoS genetics. 10 [PubMed]

Grigg P. (1986). Biophysical studies of mechanoreceptors. Journal of applied physiology (Bethesda, Md. : 1985). 60 [PubMed]

Gu Z, Eils R, Schlesner M. (2016). Complex heatmaps reveal patterns and correlations in multidimensional genomic data. Bioinformatics (Oxford, England). 32 [PubMed]

Guan D et al. (2006). Expression and biophysical properties of Kv1 channels in supragranular neocortical pyramidal neurones. The Journal of physiology. 571 [PubMed]

Gutman GA et al. (2005). International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacological reviews. 57 [PubMed]

Han L et al. (2013). A subpopulation of nociceptors specifically linked to itch. Nature neuroscience. 16 [PubMed]

Hao J, Delmas P. (2011). Recording of mechanosensitive currents using piezoelectrically driven mechanostimulator. Nature protocols. 6 [PubMed]

Harper AA, Lawson SN. (1985). Electrical properties of rat dorsal root ganglion neurones with different peripheral nerve conduction velocities. The Journal of physiology. 359 [PubMed]

Harvey AL, Robertson B. (2004). Dendrotoxins: structure-activity relationships and effects on potassium ion channels. Current medicinal chemistry. 11 [PubMed]

Heidenreich M et al. (2011). KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man. Nature neuroscience. 15 [PubMed]

Hines ML, Carnevale NT. (1997). The NEURON simulation environment. Neural computation. 9 [PubMed]

Hines ML, Carnevale NT. (2000). Expanding NEURON's repertoire of mechanisms with NMODL. Neural computation. 12 [PubMed]

Hippenmeyer S et al. (2005). A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS biology. 3 [PubMed]

Ikeda R et al. (2014). Merkel cells transduce and encode tactile stimuli to drive Aß-afferent impulses. Cell. 157 [PubMed]

Jackson AC, Bean BP. (2007). State-dependent enhancement of subthreshold A-type potassium current by 4-aminopyridine in tuberomammillary nucleus neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Jain S et al. (2006). RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Julius D. (2013). TRP channels and pain. Annual review of cell and developmental biology. 29 [PubMed]

Korngreen A, Sakmann B. (2000). Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats: subtypes and gradients. The Journal of physiology. 525 Pt 3 [PubMed]

Li CL et al. (2016). Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity. Cell research. 26 [PubMed]

Li L et al. (2011). The functional organization of cutaneous low-threshold mechanosensory neurons. Cell. 147 [PubMed]

Lien CC, Jonas P. (2003). Kv3 potassium conductance is necessary and kinetically optimized for high-frequency action potential generation in hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

Liu PW, Bean BP. (2014). Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]

Liu PW, Blair NT, Bean BP. (2017). Action Potential Broadening in Capsaicin-Sensitive DRG Neurons from Frequency-Dependent Reduction of Kv3 Current. The Journal of neuroscience : the official journal of the Society for Neuroscience. 37 [PubMed]

Love MI, Huber W, Anders S. (2014). Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome biology. 15 [PubMed]

Lu R et al. (2017). KCa3.1 channels modulate the processing of noxious chemical stimuli in mice. Neuropharmacology. 125 [PubMed]

Löken LS, Wessberg J, Morrison I, McGlone F, Olausson H. (2009). Coding of pleasant touch by unmyelinated afferents in humans. Nature neuroscience. 12 [PubMed]

Maffie JK, Dvoretskova E, Bougis PE, Martin-Eauclaire MF, Rudy B. (2013). Dipeptidyl-peptidase-like-proteins confer high sensitivity to the scorpion toxin AmmTX3 to Kv4-mediated A-type K+ channels. The Journal of physiology. 591 [PubMed]

Maksimovic S, Baba Y, Lumpkin EA. (2013). Neurotransmitters and synaptic components in the Merkel cell-neurite complex, a gentle-touch receptor. Annals of the New York Academy of Sciences. 1279 [PubMed]

Maksimovic S et al. (2014). Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors. Nature. 509 [PubMed]

Marmigère F, Ernfors P. (2007). Specification and connectivity of neuronal subtypes in the sensory lineage. Nature reviews. Neuroscience. 8 [PubMed]

Martina M, Metz AE, Bean BP. (2007). Voltage-dependent potassium currents during fast spikes of rat cerebellar Purkinje neurons: inhibition by BDS-I toxin. Journal of neurophysiology. 97 [PubMed]

Matsuyoshi H et al. (2012). Distinct cellular distributions of Kv4 pore-forming and auxiliary subunits in rat dorsal root ganglion neurons. Life sciences. 91 [PubMed]

McCarter GC, Reichling DB, Levine JD. (1999). Mechanical transduction by rat dorsal root ganglion neurons in vitro. Neuroscience letters. 273 [PubMed]

Molineux ML, Fernandez FR, Mehaffey WH, Turner RW. (2005). A-type and T-type currents interact to produce a novel spike latency-voltage relationship in cerebellar stellate cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Muqeem T, Ghosh B, Pinto V, Lepore AC, Covarrubias M. (2018). Regulation of Nociceptive Glutamatergic Signaling by Presynaptic Kv3.4 Channels in the Rat Spinal Dorsal Horn. The Journal of neuroscience : the official journal of the Society for Neuroscience. 38 [PubMed]

Osteen JD et al. (2016). Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. 534 [PubMed]

Pathak D, Guan D, Foehring RC. (2016). Roles of specific Kv channel types in repolarization of the action potential in genetically identified subclasses of pyramidal neurons in mouse neocortex. Journal of neurophysiology. 115 [PubMed]

Patil MJ, Hovhannisyan AH, Akopian AN. (2018). Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines. PloS one. 13 [PubMed]

Paul A et al. (2017). Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity. Cell. 171 [PubMed]

Petruska JC, Napaporn J, Johnson RD, Gu JG, Cooper BY. (2000). Subclassified acutely dissociated cells of rat DRG: histochemistry and patterns of capsaicin-, proton-, and ATP-activated currents. Journal of neurophysiology. 84 [PubMed]

Ranade SS, Syeda R, Patapoutian A. (2015). Mechanically Activated Ion Channels. Neuron. 87 [PubMed]

Rau KK, Petruska JC, Cooper BY, Johnson RD. (2014). Distinct subclassification of DRG neurons innervating the distal colon and glans penis/distal urethra based on the electrophysiological current signature. Journal of neurophysiology. 112 [PubMed]

Rhodes TH, Lossin C, Vanoye CG, Wang DW, George AL. (2004). Noninactivating voltage-gated sodium channels in severe myoclonic epilepsy of infancy. Proceedings of the National Academy of Sciences of the United States of America. 101 [PubMed]

Ritter DM, Ho C, O'Leary ME, Covarrubias M. (2012). Modulation of Kv3.4 channel N-type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons. The Journal of physiology. 590 [PubMed]

Ritter DM et al. (2015). Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35 [PubMed]

Royeck M et al. (2008). Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons. Journal of neurophysiology. 100 [PubMed]

Rudomin P. (1999). Presynaptic selection of afferent inflow in the spinal cord. Journal of physiology, Paris. 93 [PubMed]

Rutlin M et al. (2014). The cellular and molecular basis of direction selectivity of Ad-LTMRs. Cell. 159 [PubMed]

Sando R et al. (2013). Inducible control of gene expression with destabilized Cre. Nature methods. 10 [PubMed]

Schwarz JR, Eikhof G. (1987). Na currents and action potentials in rat myelinated nerve fibres at 20 and 37 degrees C. Pflugers Archiv : European journal of physiology. 409 [PubMed]

Shibata R et al. (2000). A-type K+ current mediated by the Kv4 channel regulates the generation of action potential in developing cerebellar granule cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Sundt D, Gamper N, Jaffe DB. (2015). Spike propagation through the dorsal root ganglia in an unmyelinated sensory neuron: a modeling study. Journal of neurophysiology. 114 [PubMed]

Südhof TC. (2012). The presynaptic active zone. Neuron. 75 [PubMed]

Trimmer JS. (2015). Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity. Neuron. 85 [PubMed]

Tsantoulas C, McMahon SB. (2014). Opening paths to novel analgesics: the role of potassium channels in chronic pain. Trends in neurosciences. 37 [PubMed]

Usoskin D et al. (2015). Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing. Nature neuroscience. 18 [PubMed]

Vacher H, Mohapatra DP, Trimmer JS. (2008). Localization and targeting of voltage-dependent ion channels in mammalian central neurons. Physiological reviews. 88 [PubMed]

Vydyanathan A, Wu ZZ, Chen SR, Pan HL. (2005). A-type voltage-gated K+ currents influence firing properties of isolectin B4-positive but not isolectin B4-negative primary sensory neurons. Journal of neurophysiology. 93 [PubMed]

Wang R, Lewin GR. (2011). The Cav3.2 T-type calcium channel regulates temporal coding in mouse mechanoreceptors. The Journal of physiology. 589 [PubMed]

Waxman SG, Zamponi GW. (2014). Regulating excitability of peripheral afferents: emerging ion channel targets. Nature neuroscience. 17 [PubMed]

Wellnitz SA, Lesniak DR, Gerling GJ, Lumpkin EA. (2010). The regularity of sustained firing reveals two populations of slowly adapting touch receptors in mouse hairy skin. Journal of neurophysiology. 103 [PubMed]

Willis WD, Coggeshall RE. (2004). Sensory Mechanisms of the Spinal Cord: Ascending Sensory Tracts and Their Descending Control .

Woo SH et al. (2014). Piezo2 is required for Merkel-cell mechanotransduction. Nature. 509 [PubMed]

Woolf CJ, Ma Q. (2007). Nociceptors--noxious stimulus detectors. Neuron. 55 [PubMed]

Zhang XL, Mok LP, Katz EJ, Gold MS. (2010). BKCa currents are enriched in a subpopulation of adult rat cutaneous nociceptive dorsal root ganglion neurons. The European journal of neuroscience. 31 [PubMed]

Zimmerman A, Bai L, Ginty DD. (2014). The gentle touch receptors of mammalian skin. Science (New York, N.Y.). 346 [PubMed]

Zimmerman AL et al. (2019). Distinct Modes of Presynaptic Inhibition of Cutaneous Afferents and Their Functions in Behavior. Neuron. 102 [PubMed]

Zylka MJ, Rice FL, Anderson DJ. (2005). Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd. Neuron. 45 [PubMed]

References and models that cite this paper
This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.