Ca2+-activated I_CAN and synaptic depression promotes network-dependent oscil. (Rubin et al. 2009)


Rubin JE, Hayes JA, Mendenhall JL, Del Negro CA. (2009). Calcium-activated nonspecific cation current and synaptic depression promote network-dependent burst oscillations. Proceedings of the National Academy of Sciences of the United States of America. 106 [PubMed]

See more from authors: Rubin JE · Hayes JA · Mendenhall JL · Del Negro CA

References and models cited by this paper

Angstadt JD, Friesen WO. (1991). Synchronized oscillatory activity in leech neurons induced by calcium channel blockers. Journal of neurophysiology. 66 [PubMed]

Ballerini L, Bracci E, Nistri A. (1997). Pharmacological block of the electrogenic sodium pump disrupts rhythmic bursting induced by strychnine and bicuculline in the neonatal rat spinal cord. Journal of neurophysiology. 77 [PubMed]

Bean BP. (2007). The action potential in mammalian central neurons. Nature reviews. Neuroscience. 8 [PubMed]

Berkowitz A. (2008). Physiology and morphology of shared and specialized spinal interneurons for locomotion and scratching. Journal of neurophysiology. 99 [PubMed]

Bertram R, Butte MJ, Kiemel T, Sherman A. (1995). Topological and phenomenological classification of bursting oscillations. Bulletin of mathematical biology. 57 [PubMed]

Brockhaus J, Ballanyi K. (1998). Synaptic inhibition in the isolated respiratory network of neonatal rats. The European journal of neuroscience. 10 [PubMed]

Brody DL, Yue DT. (2000). Release-independent short-term synaptic depression in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Butera RJ, Rinzel J, Smith JC. (1999). Models of respiratory rhythm generation in the pre-Bötzinger complex. I. Bursting pacemaker neurons. Journal of neurophysiology. 82 [PubMed]

Butera RJ, Rinzel J, Smith JC. (1999). Models of respiratory rhythm generation in the pre-Bötzinger complex. II. Populations Of coupled pacemaker neurons. Journal of neurophysiology. 82 [PubMed]

Darbon P, Tscherter A, Yvon C, Streit J. (2003). Role of the electrogenic Na/K pump in disinhibition-induced bursting in cultured spinal networks. Journal of neurophysiology. 90 [PubMed]

Darbon P, Yvon C, Legrand JC, Streit J. (2004). INaP underlies intrinsic spiking and rhythm generation in networks of cultured rat spinal cord neurons. The European journal of neuroscience. 20 [PubMed]

Del Negro CA, Koshiya N, Butera RJ, Smith JC. (2002). Persistent sodium current, membrane properties and bursting behavior of pre-bötzinger complex inspiratory neurons in vitro. Journal of neurophysiology. 88 [PubMed]

Del Negro CA, Morgado-Valle C, Feldman JL. (2002). Respiratory rhythm: an emergent network property? Neuron. 34 [PubMed]

Del Negro CA et al. (2005). Sodium and calcium current-mediated pacemaker neurons and respiratory rhythm generation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Dobrunz LE, Huang EP, Stevens CF. (1997). Very short-term plasticity in hippocampal synapses. Proceedings of the National Academy of Sciences of the United States of America. 94 [PubMed]

Ermentrout B, Dutta-moscato J, Pinto D. (2005). Bursting: The genesis of rhythm in the nervous system.

Feldman JL, Del Negro CA. (2006). Looking for inspiration: new perspectives on respiratory rhythm. Nature reviews. Neuroscience. 7 [PubMed]

Feldman JL, Smith JC. (1989). Cellular mechanisms underlying modulation of breathing pattern in mammals. Annals of the New York Academy of Sciences. 563 [PubMed]

Forsythe ID, Tsujimoto T, Barnes-Davies M, Cuttle MF, Takahashi T. (1998). Inactivation of presynaptic calcium current contributes to synaptic depression at a fast central synapse. Neuron. 20 [PubMed]

Fransén E, Tahvildari B, Egorov AV, Hasselmo ME, Alonso AA. (2006). Mechanism of graded persistent cellular activity of entorhinal cortex layer v neurons. Neuron. 49 [PubMed]

Gosgnach S et al. (2006). V1 spinal neurons regulate the speed of vertebrate locomotor outputs. Nature. 440 [PubMed]

Grillner S. (2006). Biological pattern generation: the cellular and computational logic of networks in motion. Neuron. 52 [PubMed]

Johnson SW, Seutin V, North RA. (1992). Burst firing in dopamine neurons induced by N-methyl-D-aspartate: role of electrogenic sodium pump. Science (New York, N.Y.). 258 [PubMed]

Koizumi H, Smith JC. (2008). Persistent Na+ and K+-dominated leak currents contribute to respiratory rhythm generation in the pre-Bötzinger complex in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]

Kopell N, Ermentrout GB. (1986). Parabolic bursting in an excitable system coupled with a slow oscillation. Siam J Appl Math. 46

Kosmidis EK, Pierrefiche O, Vibert JF. (2004). Respiratory-like rhythmic activity can be produced by an excitatory network of non-pacemaker neuron models. Journal of neurophysiology. 92 [PubMed]

Marder E. (2001). Moving rhythms. Nature. 410 [PubMed]

Mironov SL. (2008). Metabotropic glutamate receptors activate dendritic calcium waves and TRPM channels which drive rhythmic respiratory patterns in mice. The Journal of physiology. 586 [PubMed]

Onimaru H, Arata A, Homma I. (1997). Neuronal mechanisms of respiratory rhythm generation: an approach using in vitro preparation. The Japanese journal of physiology. 47 [PubMed]

Pace RW, Del Negro CA. (2008). AMPA and metabotropic glutamate receptors cooperatively generate inspiratory-like depolarization in mouse respiratory neurons in vitro. The European journal of neuroscience. 28 [PubMed]

Pace RW, Mackay DD, Feldman JL, Del Negro CA. (2007). Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice. The Journal of physiology. 582 [PubMed]

Pace RW, Mackay DD, Feldman JL, Del Negro CA. (2007). Role of persistent sodium current in mouse preBötzinger Complex neurons and respiratory rhythm generation. The Journal of physiology. 580 [PubMed]

Paton JF. (1997). Rhythmic bursting of pre- and post-inspiratory neurones during central apnoea in mature mice. J Physiol. 502 ( Pt 3)

Paton JF, Abdala AP, Koizumi H, Smith JC, St-John WM. (2006). Respiratory rhythm generation during gasping depends on persistent sodium current. Nature neuroscience. 9 [PubMed]

Peña F, Parkis MA, Tryba AK, Ramirez JM. (2004). Differential contribution of pacemaker properties to the generation of respiratory rhythms during normoxia and hypoxia. Neuron. 43 [PubMed]

Ptak K et al. (2005). Sodium currents in medullary neurons isolated from the pre-Bötzinger complex region. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Purvis LK, Smith JC, Koizumi H, Butera RJ. (2007). Intrinsic bursters increase the robustness of rhythm generation in an excitatory network. Journal of neurophysiology. 97 [PubMed]

Rekling JC, Champagnat J, Denavit-Saubié M. (1996). Electroresponsive properties and membrane potential trajectories of three types of inspiratory neurons in the newborn mouse brain stem in vitro. Journal of neurophysiology. 75 [PubMed]

Rekling JC, Feldman JL. (1997). Calcium-dependent plateau potentials in rostral ambiguus neurons in the newborn mouse brain stem in vitro. Journal of neurophysiology. 78 [PubMed]

Rekling JC, Feldman JL. (1998). PreBötzinger complex and pacemaker neurons: hypothesized site and kernel for respiratory rhythm generation. Annual review of physiology. 60 [PubMed]

Rinzel JA. (1987). A formal classification of bursting mechanisms in excitable systems Proc Intl Congress Mathematicians.

Rubin J. (2006). Bursting inducedbyexcitatory synaptic coupling in nonidentical conditional relaxation oscillators or square-wave bursters Phys Rev E. 74

Schwarzacher SW, Wilhelm Z, Anders K, Richter DW. (1991). The medullary respiratory network in the rat. The Journal of physiology. 435 [PubMed]

Smith JC, Abdala AP, Koizumi H, Rybak IA, Paton JF. (2007). Spatial and functional architecture of the mammalian brain stem respiratory network: a hierarchy of three oscillatory mechanisms. Journal of neurophysiology. 98 [PubMed]

Smith JC, Ellenberger HH, Ballanyi K, Richter DW, Feldman JL. (1991). Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science (New York, N.Y.). 254 [PubMed]

Tazerart S, Viemari JC, Darbon P, Vinay L, Brocard F. (2007). Contribution of persistent sodium current to locomotor pattern generation in neonatal rats. Journal of neurophysiology. 98 [PubMed]

Terman D, Rubin J, Wechselberger M, Borisyuk A, Best J. (2005). The dynamic range of bursting in a model respiratory pacemaker network Siam J App Dyn Sys. 4

Wang D, Grillner S, Wallén P. (2006). Effects of flufenamic acid on fictive locomotion, plateau potentials, calcium channels and NMDA receptors in the lamprey spinal cord. Neuropharmacology. 51 [PubMed]

Yvon C, Czarnecki A, Streit J. (2007). Riluzole-induced oscillations in spinal networks. Journal of neurophysiology. 97 [PubMed]

Zhong G, Masino MA, Harris-Warrick RM. (2007). Persistent sodium currents participate in fictive locomotion generation in neonatal mouse spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Zhu ZT, Munhall A, Shen KZ, Johnson SW. (2004). Calcium-dependent subthreshold oscillations determine bursting activity induced by N-methyl-D-aspartate in rat subthalamic neurons in vitro. The European journal of neuroscience. 19 [PubMed]

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