Model Concept: Pathophysiology

The physiology (specific functions) associated with a condition in which the normal functioning of an animal is impaired.

  1. A dynamical model of the basal ganglia (Leblois et al 2006)
  2. A neural model of Parkinson`s disease (Cutsuridis and Perantonis 2006, Cutsuridis 2006, 2007)
  3. A systems model of Parkinson’s disease using biochemical systems theory (Sasidharakurup et al. 2017)
  4. Amyloid beta (IA block) effects on a model CA1 pyramidal cell (Morse et al. 2010)
  5. Anoxic depolarization, recovery: effect of brain regions and extracellular space (Hubel et al. 2016)
  6. Axonal spheroids and conduction defects in Alzheimer’s disease (Yuan, Zhang, Tong, et al 2022)
  7. Biologically Constrained Basal Ganglia model (BCBG model) (Lienard, Girard 2014)
  8. Breakdown of accmmodation in nerve: a possible role for INAp (Hennings et al 2005)
  9. CA3 Network Model of Epileptic Activity (Sanjay et. al, 2015)
  10. Cardiac action potential based on Luo-Rudy phase 1 model (Luo and Rudy 1991), (Wu 2004)
  11. Cardiac Atrial Cell (Courtemanche et al 1998) (C++)
  12. Computational neuropharmacology of CA1 pyramidal neuron (Ferrante et al. 2008)
  13. Cortical oscillations and the basal ganglia (Fountas & Shanahan 2017)
  14. Criticality,degeneracy in injury-induced changes in primary afferent excitability (Ratte et al 2014)
  15. Dentate gyrus network model pattern separation and granule cell scaling in epilepsy (Yim et al 2015)
  16. Dorsal root ganglion (DRG) neuronal model (Kovalsky et al. 2009)
  17. Dynamic dopamine modulation in the basal ganglia: Learning in Parkinson (Frank et al 2004,2005)
  18. Growth Rules for Repair of Asynch Irregular Networks after Peripheral Lesions (Sinha et al 2021)
  19. Huntington`s disease model (Gambazzi et al. 2010)
  20. Ketamine disrupts theta modulation of gamma in a computer model of hippocampus (Neymotin et al 2011)
  21. Markovian model for cardiac sodium channel (Clancy, Rudy 2002)
  22. Mechanisms for pattern specificity of DBS in Parkinson's disease (Velarde et al 2017)
  23. Method for counting motor units in mice (Major et al 2007)
  24. Multiscale model of excitotoxicity in PD (Muddapu and Chakravarthy 2020)
  25. Multitarget pharmacology for Dystonia in M1 (Neymotin et al 2016)
  26. Neural mass model based on single cell dynamics to model pathophysiology (Zandt et al 2014)
  27. Nicotinic control of dopamine release in nucleus accumbens (Maex et al. 2014)
  28. Nigral dopaminergic neurons: effects of ethanol on Ih (Migliore et al. 2008)
  29. Nodes of Ranvier with left-shifted Nav channels (Boucher et al. 2012)
  30. Single-cell comprehensive biophysical model of SN pars compacta (Muddapu & Chakravarthy 2021)
  31. Ventromedial Thalamocortical Neuron (Bichler et al 2021)
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Top concepts studied with Pathophysiology:
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