Cell Type: Hippocampus CA3 pyramidal GLU cell

The principal neuron of region CA3 of the hippocampus. It forms a single cell body layer. It gives rise to an apical dendritic tree and several basal dendrites, which are covered with spines. The apical shaft has thorny excresences which receive the excitatory glutamatergic synapses of the mossy fibers from the dentate granule cells. The output of the cell is carried in an axon which recurs to pass through the apical dendritic tree before becoming the Shafer collateral which has excitatory glutamatergic synapses on the apical dendrites of CA1 pyramidal neurons. The axon also makes excitatory glutamatergic synapses on the dendrites of the CA3 pyramidal neurons as it passes through them.

  1. A 1000 cell network model for Lateral Amygdala (Kim et al. 2013)
  2. A model of unitary responses from A/C and PP synapses in CA3 pyramidal cells (Baker et al. 2010)
  3. Acetylcholine Boosts Dendritic NMDA Spikes in a CA3 Pyramidal Neuron Model (Humphries et al., 2021)
  4. Actions of Rotenone on ionic currents and MEPPs in Mouse Hippocampal Neurons (Huang et al 2018)
  5. CA3 hippocampal pyramidal neuron with voltage-clamp intrinsic conductance data (Traub et al 1991)
  6. CA3 Network Model of Epileptic Activity (Sanjay et. al, 2015)
  7. CA3 pyramidal cell: rhythmogenesis in a reduced Traub model (Pinsky, Rinzel 1994)
  8. CA3 pyramidal neuron (Lazarewicz et al 2002)
  9. CA3 Pyramidal Neuron (Migliore et al 1995)
  10. CA3 pyramidal neuron (Safiulina et al. 2010)
  11. CA3 pyramidal neuron: firing properties (Hemond et al. 2008)
  12. Ca3 pyramidal neuron: membrane response near rest (Hemond et al. 2009)
  13. CA3 pyramidal neurons: Kv1.2 mediates modulation of cortical inputs (Hyun et al., 2015)
  14. Coincident glutamatergic depolarization effects on Cl- dynamics (Lombardi et al, 2021)
  15. Conductance based model for short term plasticity at CA3-CA1 synapses (Mukunda & Narayanan 2017)
  16. Dendritica (Vetter et al 2001)
  17. Extraction and classification of three cortical neuron types (Mensi et al. 2012)
  18. Factors contribution to GDP-induced [Cl-]i transients (Lombardi et al 2019)
  19. Firing patterns of CA3 hippocampal neurons (Soldado-Magraner et al. 2019)
  20. Fully continuous Pinsky-Rinzel model for bifurcation analysis (Atherton et al. 2016)
  21. Gamma and theta rythms in biophysical models of hippocampus circuits (Kopell et al. 2011)
  22. High frequency oscillations in a hippocampal computational model (Stacey et al. 2009)
  23. Hippocampal CA3 network and circadian regulation (Stanley et al. 2013)
  24. Hippocampal CA3 thorny and a-thorny principal neuron models (Linaro et al in review)
  25. Ih tunes oscillations in an In Silico CA3 model (Neymotin et al. 2013)
  26. Impact of dendritic atrophy on intrinsic and synaptic excitability (Narayanan & Chattarji, 2010)
  27. In silico hippocampal modeling for multi-target pharmacotherapy in schizophrenia (Sherif et al 2020)
  28. Ionic mechanisms of bursting in CA3 pyramidal neurons (Xu and Clancy 2008)
  29. Ketamine disrupts theta modulation of gamma in a computer model of hippocampus (Neymotin et al 2011)
  30. Long time windows from theta modulated inhib. in entorhinal–hippo. loop (Cutsuridis & Poirazi 2015)
  31. Mean Field Equations for Two-Dimensional Integrate and Fire Models (Nicola and Campbell, 2013)
  32. Mechanisms of very fast oscillations in axon networks coupled by gap junctions (Munro, Borgers 2010)
  33. Model of long range transmission of gamma oscillation (Murray 2007)
  34. Network recruitment to coherent oscillations in a hippocampal model (Stacey et al. 2011)
  35. Neuronal dendrite calcium wave model (Neymotin et al, 2015)
  36. NMDA receptors enhance the fidelity of synaptic integration (Li and Gulledge 2021)
  37. Non-Weak E-Fields Pyramidal Neurons (Reznik et. al.,2015)
  38. Region-specific atrophy in dendrites (Narayanan, Narayan, Chattarji, 2005)
  39. Role for short term plasticity and OLM cells in containing spread of excitation (Hummos et al 2014)
  40. Spatial constrains of GABAergic rheobase shift (Lombardi et al., 2021)
  41. Spiking GridPlaceMap model (Pilly & Grossberg, PLoS One, 2013)
  42. STDP and NMDAR Subunits (Gerkin et al. 2007)
  43. Synthesis of spatial tuning functions from theta cell spike trains (Welday et al., 2011)
  44. The role of ATP-sensitive potassium channels in a hippocampal neuron (Huang et al. 2007)
  45. Theta phase precession in a model CA3 place cell (Baker and Olds 2007)
  46. Zonisamide-induced inhibition of the firing of APs in hippocampal neurons (Huang et al. 2007)
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