Paradoxical effect of fAHP amplitude on gain in dentate gyrus granule cells (Jaffe & Brenner 2018)


Jaffe DB, Brenner R. (2018). A computational model for how the fast afterhyperpolarization paradoxically increases gain in regularly firing neurons. Journal of neurophysiology. 119 [PubMed]

See more from authors: Jaffe DB · Brenner R

References and models cited by this paper

ANDERSEN P, ECCLES JC, SEARS TA. (1964). THE VENTRO-BASAL COMPLEX OF THE THALAMUS: TYPES OF CELLS, THEIR RESPONSES AND THEIR FUNCTIONAL ORGANIZATION. The Journal of physiology. 174 [PubMed]

Aguado C, García-Madrona S, Gil-Minguez M, Luján R. (2016). Ontogenic Changes and Differential Localization of T-type Ca(2+) Channel Subunits Cav3.1 and Cav3.2 in Mouse Hippocampus and Cerebellum. Frontiers in neuroanatomy. 10 [PubMed]

Aizenman CD, Linden DJ. (1999). Regulation of the rebound depolarization and spontaneous firing patterns of deep nuclear neurons in slices of rat cerebellum. Journal of neurophysiology. 82 [PubMed]

Andrew RD, Dudek FE. (1983). Burst discharge in mammalian neuroendocrine cells involves an intrinsic regenerative mechanism. Science (New York, N.Y.). 221 [PubMed]

Angelo K, Margrie TW. (2011). Population diversity and function of hyperpolarization-activated current in olfactory bulb mitral cells. Scientific reports. 1 [PubMed]

Aradi I, Holmes WR. (1999). Role of multiple calcium and calcium-dependent conductances in regulation of hippocampal dentate granule cell excitability. Journal of computational neuroscience. 6 [PubMed]

Attwell D, Cohen I, Eisner D, Ohba M, Ojeda C. (1979). The steady state TTX-sensitive ("window") sodium current in cardiac Purkinje fibres. Pflugers Archiv : European journal of physiology. 379 [PubMed]

Azouz R, Jensen MS, Yaari Y. (1996). Ionic basis of spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells. The Journal of physiology. 492 ( Pt 1) [PubMed]

Barrio LC, Araque A, Buño W. (1994). Participation of voltage-gated conductances on the response succeeding inhibitory synaptic potentials in the crayfish slowly adapting stretch receptor neuron. Journal of neurophysiology. 72 [PubMed]

Bean BP. (2007). The action potential in mammalian central neurons. Nature reviews. Neuroscience. 8 [PubMed]

Beck H, Steffens R, Elger CE, Heinemann U. (1998). Voltage-dependent Ca2+ currents in epilepsy. Epilepsy research. 32 [PubMed]

Becker AJ et al. (2008). Transcriptional upregulation of Cav3.2 mediates epileptogenesis in the pilocarpine model of epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]

Benarroch EE. (2013). HCN channels: function and clinical implications. Neurology. 80 [PubMed]

Boehme R, Uebele VN, Renger JJ, Pedroarena C. (2011). Rebound excitation triggered by synaptic inhibition in cerebellar nuclear neurons is suppressed by selective T-type calcium channel block. Journal of neurophysiology. 106 [PubMed]

Borst JG, Sakmann B. (1996). Calcium influx and transmitter release in a fast CNS synapse. Nature. 383 [PubMed]

Brenner R et al. (2005). BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Nature neuroscience. 8 [PubMed]

Brãuer AU et al. (2001). Molecular and functional analysis of hyperpolarization-activated pacemaker channels in the hippocampus after entorhinal cortex lesion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15 [PubMed]

Chemin J et al. (2002). Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability. The Journal of physiology. 540 [PubMed]

Connors BW, Gutnick MJ, Prince DA. (1982). Electrophysiological properties of neocortical neurons in vitro. Journal of neurophysiology. 48 [PubMed]

Contet C, Goulding SP, Kuljis DA, Barth AL. (2016). BK Channels in the Central Nervous System. International review of neurobiology. 128 [PubMed]

Crill WE. (1996). Persistent sodium current in mammalian central neurons. Annual review of physiology. 58 [PubMed]

Crunelli V, Tóth TI, Cope DW, Blethyn K, Hughes SW. (2005). The 'window' T-type calcium current in brain dynamics of different behavioural states. The Journal of physiology. 562 [PubMed]

Deschênes M, Roy JP, Steriade M. (1982). Thalamic bursting mechanism: an inward slow current revealed by membrane hyperpolarization. Brain research. 239 [PubMed]

Dietrich D et al. (1999). Two electrophysiologically distinct types of granule cells in epileptic human hippocampus. Neuroscience. 90 [PubMed]

Du W et al. (2005). Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder. Nature genetics. 37 [PubMed]

Engbers JD et al. (2011). Distinct roles for I(T) and I(H) in controlling the frequency and timing of rebound spike responses. The Journal of physiology. 589 [PubMed]

Epsztein J, Sola E, Represa A, Ben-Ari Y, Crépel V. (2010). A selective interplay between aberrant EPSPKA and INaP reduces spike timing precision in dentate granule cells of epileptic rats. Cerebral cortex (New York, N.Y. : 1991). 20 [PubMed]

Erisir A, Lau D, Rudy B, Leonard CS. (1999). Function of specific K(+) channels in sustained high-frequency firing of fast-spiking neocortical interneurons. Journal of neurophysiology. 82 [PubMed]

Ermentrout B. (1996). Type I membranes, phase resetting curves, and synchrony. Neural computation. 8 [PubMed]

Ermentrout GB, Glass L, Butera R, Krogh-Madsen T. (2012). Phase Response Curves in Neuroscience.

Fernandez FR, Mehaffey WH, Turner RW. (2005). Dendritic Na+ current inactivation can increase cell excitability by delaying a somatic depolarizing afterpotential. Journal of neurophysiology. 94 [PubMed]

Foehring RC, Mermelstein PG, Song WJ, Ulrich S, Surmeier DJ. (2000). Unique properties of R-type calcium currents in neocortical and neostriatal neurons. Journal of neurophysiology. 84 [PubMed]

Fricke RA, Prince DA. (1984). Electrophysiology of dentate gyrus granule cells. Journal of neurophysiology. 51 [PubMed]

Gauss R, Seifert R. (2000). Pacemaker oscillations in heart and brain: a key role for hyperpolarization-activated cation channels. Chronobiology international. 17 [PubMed]

Gerasimov VD, Kostyuk PG, Maiskii VA. (1966). Reactions of giant neurons to break of hyperpolarizing current. Federation proceedings. Translation supplement; selected translations from medical-related science. 25 [PubMed]

Giese KP et al. (1998). Reduced K+ channel inactivation, spike broadening, and after-hyperpolarization in Kvbeta1.1-deficient mice with impaired learning. Learning & memory (Cold Spring Harbor, N.Y.). 5 [PubMed]

Golomb D, Yue C, Yaari Y. (2006). Contribution of persistent Na+ current and M-type K+ current to somatic bursting in CA1 pyramidal cells: combined experimental and modeling study. Journal of neurophysiology. 96 [PubMed]

Gray LS, Macdonald TL. (2006). The pharmacology and regulation of T type calcium channels: new opportunities for unique therapeutics for cancer. Cell calcium. 40 [PubMed]

Gu N, Vervaeke K, Storm JF. (2007). BK potassium channels facilitate high-frequency firing and cause early spike frequency adaptation in rat CA1 hippocampal pyramidal cells. The Journal of physiology. 580 [PubMed]

Guo F et al. (2013). The up-regulation of voltage-gated sodium channels subtypes coincides with an increased sodium current in hippocampal neuronal culture model. Neurochemistry international. 62 [PubMed]

Haj-Dahmane S, Andrade R. (1997). Calcium-activated cation nonselective current contributes to the fast afterdepolarization in rat prefrontal cortex neurons. Journal of neurophysiology. 78 [PubMed]

Harris KD, Hirase H, Leinekugel X, Henze DA, Buzsáki G. (2001). Temporal interaction between single spikes and complex spike bursts in hippocampal pyramidal cells. Neuron. 32 [PubMed]

Hartline DK, Gassie DV. (1979). Pattern generation in the lobster (Panulirus) stomatogastric ganglion. I. Pyloric neuron kinetics and synaptic interactions. Biological cybernetics. 33 [PubMed]

Hines ML, Carnevale NT. (1997). The NEURON simulation environment. Neural computation. 9 [PubMed]

Hines ML, Carnevale NT. (2000). Expanding NEURON's repertoire of mechanisms with NMODL. Neural computation. 12 [PubMed]

Hodgkin AL. (1948). The local electric changes associated with repetitive action in a non-medullated axon. The Journal of physiology. 107 [PubMed]

Hughes SW et al. (2008). Novel modes of rhythmic burst firing at cognitively-relevant frequencies in thalamocortical neurons. Brain research. 1235 [PubMed]

Huguenard JR, McCormick DA. (1992). Simulation of the currents involved in rhythmic oscillations in thalamic relay neurons. Journal of neurophysiology. 68 [PubMed]

Jaffe DB, Wang B, Brenner R. (2011). Shaping of action potentials by type I and type II large-conductance Ca²+-activated K+ channels. Neuroscience. 192 [PubMed]

Jahnsen H, Llinás R. (1984). Ionic basis for the electro-responsiveness and oscillatory properties of guinea-pig thalamic neurones in vitro. The Journal of physiology. 349 [PubMed]

Jahnsen H, Llinás R. (1984). Voltage-dependent burst-to-tonic switching of thalamic cell activity: an in vitro study. Archives italiennes de biologie. 122 [PubMed]

Jensen MS, Azouz R, Yaari Y. (1996). Spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells. The Journal of physiology. 492 ( Pt 1) [PubMed]

Jin W, Sugaya A, Tsuda T, Ohguchi H, Sugaya E. (2000). Relationship between large conductance calcium-activated potassium channel and bursting activity. Brain research. 860 [PubMed]

KANDEL ER, SPENCER WA. (1961). Electrophysiology of hippocampal neurons. II. After-potentials and repetitive firing. Journal of neurophysiology. 24 [PubMed]

KUFFLER SW, EYZAGUIRRE C. (1955). Synaptic inhibition in an isolated nerve cell. The Journal of general physiology. 39 [PubMed]

Kandel ER, Castellucci VF, Shapiro E. (1980). Presynaptic membrane potential affects transmitter release in an identified neuron in Aplysia by modulating the Ca2+ and K+ currents. Proc Natl Acad Sci U S A. 77

Kirchheim F, Tinnes S, Haas CA, Stegen M, Wolfart J. (2013). Regulation of action potential delays via voltage-gated potassium Kv1.1 channels in dentate granule cells during hippocampal epilepsy. Frontiers in cellular neuroscience. 7 [PubMed]

Klein M, Camardo J, Kandel ER. (1982). Serotonin modulates a specific potassium current in the sensory neurons that show presynaptic facilitation in Aplysia. Proceedings of the National Academy of Sciences of the United States of America. 79 [PubMed]

Koschak A et al. (2001). alpha 1D (Cav1.3) subunits can form l-type Ca2+ channels activating at negative voltages. The Journal of biological chemistry. 276 [PubMed]

Kress GJ, Dowling MJ, Eisenman LN, Mennerick S. (2010). Axonal sodium channel distribution shapes the depolarized action potential threshold of dentate granule neurons. Hippocampus. 20 [PubMed]

Kress GJ, Dowling MJ, Meeks JP, Mennerick S. (2008). High threshold, proximal initiation, and slow conduction velocity of action potentials in dentate granule neuron mossy fibers. Journal of neurophysiology. 100 [PubMed]

Krueppel R, Remy S, Beck H. (2011). Dendritic integration in hippocampal dentate granule cells. Neuron. 71 [PubMed]

LaPage MJ, Russell MW, Bradley DJ, Dick M. (2012). Novel ryanodine receptor 2 mutation associated with a severe phenotype of catecholaminergic polymorphic ventricular tachycardia. The Journal of pediatrics. 161 [PubMed]

Lazarewicz MT, Migliore M, Ascoli GA. (2002). A new bursting model of CA3 pyramidal cell physiology suggests multiple locations for spike initiation. Bio Systems. 67 [PubMed]

Lehnart SE et al. (2008). Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. The Journal of clinical investigation. 118 [PubMed]

Lemon N, Turner RW. (2000). Conditional spike backpropagation generates burst discharge in a sensory neuron. Journal of neurophysiology. 84 [PubMed]

Lien CC, Jonas P. (2003). Kv3 potassium conductance is necessary and kinetically optimized for high-frequency action potential generation in hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

Lin M, Hatcher JT, Wurster RD, Chen QH, Cheng ZJ. (2014). Characteristics of single large-conductance Ca2+-activated K+ channels and their regulation of action potentials and excitability in parasympathetic cardiac motoneurons in the nucleus ambiguus. American journal of physiology. Cell physiology. 306 [PubMed]

Lisman JE. (1997). Bursts as a unit of neural information: making unreliable synapses reliable. Trends in neurosciences. 20 [PubMed]

Llinás R, Mühlethaler M. (1988). An electrophysiological study of the in vitro, perfused brain stem-cerebellum of adult guinea-pig. The Journal of physiology. 404 [PubMed]

Llinás R, Steinberg IZ, Walton K. (1976). Presynaptic calcium currents and their relation to synaptic transmission: voltage clamp study in squid giant synapse and theoretical model for the calcium gate. Proceedings of the National Academy of Sciences of the United States of America. 73 [PubMed]

Llinás R, Yarom Y. (1981). Properties and distribution of ionic conductances generating electroresponsiveness of mammalian inferior olivary neurones in vitro. The Journal of physiology. 315 [PubMed]

Ly C, Melman T, Barth AL, Ermentrout GB. (2011). Phase-resetting curve determines how BK currents affect neuronal firing. Journal of computational neuroscience. 30 [PubMed]

Magee JC, Carruth M. (1999). Dendritic voltage-gated ion channels regulate the action potential firing mode of hippocampal CA1 pyramidal neurons. Journal of neurophysiology. 82 [PubMed]

Magistretti J, Castelli L, Forti L, D'Angelo E. (2006). Kinetic and functional analysis of transient, persistent and resurgent sodium currents in rat cerebellar granule cells in situ: an electrophysiological and modelling study. The Journal of physiology. 573 [PubMed]

Mainen ZF, Sejnowski TJ. (1995). Reliability of spike timing in neocortical neurons. Science (New York, N.Y.). 268 [PubMed]

Mainen ZF, Sejnowski TJ. (1996). Influence of dendritic structure on firing pattern in model neocortical neurons. Nature. 382 [PubMed]

Martina M, Schultz JH, Ehmke H, Monyer H, Jonas P. (1998). Functional and molecular differences between voltage-gated K+ channels of fast-spiking interneurons and pyramidal neurons of rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

Martinello K et al. (2015). Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells. Neuron. 85 [PubMed]

Matthews EA, Weible AP, Shah S, Disterhoft JF. (2008). The BK-mediated fAHP is modulated by learning a hippocampus-dependent task. Proceedings of the National Academy of Sciences of the United States of America. 105 [PubMed]

McKay BE et al. (2006). Ca(V)3 T-type calcium channel isoforms differentially distribute to somatic and dendritic compartments in rat central neurons. The European journal of neuroscience. 24 [PubMed]

McKay BE, Turner RW. (2004). Kv3 K+ channels enable burst output in rat cerebellar Purkinje cells. The European journal of neuroscience. 20 [PubMed]

Mehaffey WH, Fernandez FR, Doiron B, Turner RW. (2008). Regulation of somatic firing dynamics by backpropagating dendritic spikes. Journal of physiology, Paris. 102 [PubMed]

Mehranfard N, Gholamipour-Badie H, Motamedi F, Janahmadi M, Naderi N. (2014). The effect of paxilline on early alterations of electrophysiological properties of dentate gyrus granule cells in pilocarpine-treated rats. Iranian journal of pharmaceutical research : IJPR. 13 [PubMed]

Mehranfard N, Gholamipour-Badie H, Motamedi F, Janahmadi M, Naderi N. (2015). Long-term increases in BK potassium channel underlie increased action potential firing in dentate granule neurons following pilocarpine-induced status epilepticus in rats. Neuroscience letters. 585 [PubMed]

Meredith AL et al. (2006). BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output. Nature neuroscience. 9 [PubMed]

Metz AE, Jarsky T, Martina M, Spruston N. (2005). R-type calcium channels contribute to afterdepolarization and bursting in hippocampal CA1 pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Mitra P, Miller RF. (2007). Mechanism underlying rebound excitation in retinal ganglion cells. Visual neuroscience. 24 [PubMed]

Morisset V, Nagy F. (1999). Ionic basis for plateau potentials in deep dorsal horn neurons of the rat spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Nagrani T, Siyamwala M, Vahid G, Bekheit S. (2011). Ryanodine calcium channel: a novel channelopathy for seizures. The neurologist. 17 [PubMed]

Nelson AB, Krispel CM, Sekirnjak C, du Lac S. (2003). Long-lasting increases in intrinsic excitability triggered by inhibition. Neuron. 40 [PubMed]

Pedroarena CM. (2010). Mechanisms supporting transfer of inhibitory signals into the spike output of spontaneously firing cerebellar nuclear neurons in vitro. Cerebellum (London, England). 9 [PubMed]

Pitts GR, Ohta H, McMahon DG. (2006). Daily rhythmicity of large-conductance Ca2+ -activated K+ currents in suprachiasmatic nucleus neurons. Brain research. 1071 [PubMed]

Putzier I, Kullmann PH, Horn JP, Levitan ES. (2009). Cav1.3 channel voltage dependence, not Ca2+ selectivity, drives pacemaker activity and amplifies bursts in nigral dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Rama S et al. (2017). The role of axonal Kv1 channels in CA3 pyramidal cell excitability. Scientific reports. 7 [PubMed]

Ranck JB. (1973). Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires. Experimental neurology. 41 [PubMed]

Razani-Boroujerdi S, Partridge LD. (1993). Activation and modulation of calcium-activated non-selective cation channels from embryonic chick sensory neurons. Brain research. 623 [PubMed]

Robinson RB, Siegelbaum SA. (2003). Hyperpolarization-activated cation currents: from molecules to physiological function. Annual review of physiology. 65 [PubMed]

Ropireddy D, Scorcioni R, Lasher B, Buzsáki G, Ascoli GA. (2011). Axonal morphometry of hippocampal pyramidal neurons semi-automatically reconstructed after in vivo labeling in different CA3 locations. Brain structure & function. 216 [PubMed]

Rudy B et al. (1999). Contributions of Kv3 channels to neuronal excitability. Annals of the New York Academy of Sciences. 868 [PubMed]

Rudy B, McBain CJ. (2001). Kv3 channels: voltage-gated K+ channels designed for high-frequency repetitive firing. Trends in neurosciences. 24 [PubMed]

Sabatini BL, Regehr WG. (1997). Control of neurotransmitter release by presynaptic waveform at the granule cell to Purkinje cell synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]

Safa P, Boulter J, Hales TG. (2001). Functional properties of Cav1.3 (alpha1D) L-type Ca2+ channel splice variants expressed by rat brain and neuroendocrine GH3 cells. The Journal of biological chemistry. 276 [PubMed]

Sah P. (1996). Ca(2+)-activated K+ currents in neurones: types, physiological roles and modulation. Trends in neurosciences. 19 [PubMed]

Sah P, Faber ES. (2002). Channels underlying neuronal calcium-activated potassium currents. Progress in neurobiology. 66 [PubMed]

Sangrey T, Jaeger D. (2010). Analysis of distinct short and prolonged components in rebound spiking of deep cerebellar nucleus neurons. The European journal of neuroscience. 32 [PubMed]

Santoro B et al. (2000). Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Schmidt-Hieber C, Bischofberger J. (2010). Fast sodium channel gating supports localized and efficient axonal action potential initiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]

Schmidt-Hieber C, Jonas P, Bischofberger J. (2007). Subthreshold dendritic signal processing and coincidence detection in dentate gyrus granule cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Schmidt-Hieber C, Jonas P, Bischofberger J. (2008). Action potential initiation and propagation in hippocampal mossy fibre axons. The Journal of physiology. 586 [PubMed]

Sekirnjak C et al. (1997). Subcellular localization of the K+ channel subunit Kv3.1b in selected rat CNS neurons. Brain research. 766 [PubMed]

Selke K, Müller A, Kukley M, Schramm J, Dietrich D. (2006). Firing pattern and calbindin-D28k content of human epileptic granule cells. Brain research. 1120 [PubMed]

Selverston AI, Russell DF, Miller JP. (1976). The stomatogastric nervous system: structure and function of a small neural network. Progress in neurobiology. 7 [PubMed]

Shao LR, Halvorsrud R, Borg-Graham L, Storm JF. (1999). The role of BK-type Ca2+-dependent K+ channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells. The Journal of physiology. 521 Pt 1 [PubMed]

Shruti S, Clem RL, Barth AL. (2008). A seizure-induced gain-of-function in BK channels is associated with elevated firing activity in neocortical pyramidal neurons. Neurobiology of disease. 30 [PubMed]

Sochivko D et al. (2002). The Ca(V)2.3 Ca(2+) channel subunit contributes to R-type Ca(2+) currents in murine hippocampal and neocortical neurones. The Journal of physiology. 542 [PubMed]

Spruston N, Johnston D. (1992). Perforated patch-clamp analysis of the passive membrane properties of three classes of hippocampal neurons. Journal of neurophysiology. 67 [PubMed]

Stabel J, Ficker E, Heinemann U. (1992). Young CA1 pyramidal cells of rats, but not dentate gyrus granule cells, express a delayed inward rectifying current with properties of IQ. Neuroscience letters. 135 [PubMed]

Stegen M et al. (2012). Adaptive intrinsic plasticity in human dentate gyrus granule cells during temporal lobe epilepsy. Cerebral cortex (New York, N.Y. : 1991). 22 [PubMed]

Stegen M, Young CC, Haas CA, Zentner J, Wolfart J. (2009). Increased leak conductance in dentate gyrus granule cells of temporal lobe epilepsy patients with Ammon's horn sclerosis. Epilepsia. 50 [PubMed]

Storm JF. (1987). Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells. The Journal of physiology. 385 [PubMed]

Storm JF. (1990). Potassium currents in hippocampal pyramidal cells. Progress in brain research. 83 [PubMed]

Suzuki SS, Smith GK. (1985). Burst characteristics of hippocampal complex spike cells in the awake rat. Experimental neurology. 89 [PubMed]

Swensen AM, Bean BP. (2003). Ionic mechanisms of burst firing in dissociated Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

Tadayonnejad R, Mehaffey WH, Anderson D, Turner RW. (2009). Reliability of triggering postinhibitory rebound bursts in deep cerebellar neurons. Channels (Austin, Tex.). 3 [PubMed]

Taddese A, Bean BP. (2002). Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons. Neuron. 33 [PubMed]

Talley EM et al. (1999). Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Tang AC, Bartels AM, Sejnowski TJ. (1997). Effects of cholinergic modulation on responses of neocortical neurons to fluctuating input. Cerebral cortex (New York, N.Y. : 1991). 7 [PubMed]

Turner RW, Maler L, Deerinck T, Levinson SR, Ellisman MH. (1994). TTX-sensitive dendritic sodium channels underlie oscillatory discharge in a vertebrate sensory neuron. The Journal of neuroscience : the official journal of the Society for Neuroscience. 14 [PubMed]

Wahl-Schott C, Biel M. (2009). HCN channels: structure, cellular regulation and physiological function. Cellular and molecular life sciences : CMLS. 66 [PubMed]

Wang B et al. (2016). Knockout of the BK ß4-subunit promotes a functional coupling of BK channels and ryanodine receptors that mediate a fAHP-induced increase in excitability. Journal of neurophysiology. 116 [PubMed]

Wang B, Rothberg BS, Brenner R. (2006). Mechanism of beta4 subunit modulation of BK channels. The Journal of general physiology. 127 [PubMed]

Wang LY, Gan L, Forsythe ID, Kaczmarek LK. (1998). Contribution of the Kv3.1 potassium channel to high-frequency firing in mouse auditory neurones. The Journal of physiology. 509 ( Pt 1) [PubMed]

Wang XX et al. (2016). Characterization of Rebound Depolarization in Neurons of the Rat Medial Geniculate Body In Vitro. Neuroscience bulletin. 32 [PubMed]

Wehrens XH et al. (2003). FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell. 113 [PubMed]

White G, Lovinger DM, Weight FF. (1989). Transient low-threshold Ca2+ current triggers burst firing through an afterdepolarizing potential in an adult mammalian neuron. Proceedings of the National Academy of Sciences of the United States of America. 86 [PubMed]

Williams SR, Stuart GJ. (1999). Mechanisms and consequences of action potential burst firing in rat neocortical pyramidal neurons. The Journal of physiology. 521 Pt 2 [PubMed]

Williamson A. (1994). Electrophysiology of epileptic human neocortical andhippocampal neurons maintained in vitro Clin Neurosci. 2

Wolfart J, Laker D. (2015). Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potential. Frontiers in physiology. 6 [PubMed]

Xu W, Lipscombe D. (2001). Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]

Young CC et al. (2009). Upregulation of inward rectifier K+ (Kir2) channels in dentate gyrus granule cells in temporal lobe epilepsy. The Journal of physiology. 587 [PubMed]

Yue C, Remy S, Su H, Beck H, Yaari Y. (2005). Proximal persistent Na+ channels drive spike afterdepolarizations and associated bursting in adult CA1 pyramidal cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Yue C, Yaari Y. (2006). Axo-somatic and apical dendritic Kv7/M channels differentially regulate the intrinsic excitability of adult rat CA1 pyramidal cells. Journal of neurophysiology. 95 [PubMed]

Yuen GL, Durand D. (1991). Reconstruction of hippocampal granule cell electrophysiology by computer simulation. Neuroscience. 41 [PubMed]

Yunker AM et al. (2003). Immunological characterization of T-type voltage-dependent calcium channel CaV3.1 (alpha 1G) and CaV3.3 (alpha 1I) isoforms reveal differences in their localization, expression, and neural development. Neuroscience. 117 [PubMed]

Zhang L, Valiante TA, Carlen PL. (1993). Contribution of the low-threshold T-type calcium current in generating the post-spike depolarizing afterpotential in dentate granule neurons of immature rats. Journal of neurophysiology. 70 [PubMed]

Zheng N, Raman IM. (2009). Ca currents activated by spontaneous firing and synaptic disinhibition in neurons of the cerebellar nuclei. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Zhu ZT, Munhall A, Shen KZ, Johnson SW. (2004). Calcium-dependent subthreshold oscillations determine bursting activity induced by N-methyl-D-aspartate in rat subthalamic neurons in vitro. The European journal of neuroscience. 19 [PubMed]

References and models that cite this paper
This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.