Model Concept: Heart disease

Heart diseases are illnesses caused by abnormalities either of the heart or of the circulation of blood or both.

  1. A cardiac cell simulator (Puglisi and Bers 2001), applied to the QT interval (Busjahn et al 2004)
  2. A dynamic model of the canine ventricular myocyte (Hund, Rudy 2004)
  3. Cardiac action potential based on Luo-Rudy phase 1 model (Luo and Rudy 1991), (Wu 2004)
  4. Cardiac Atrial Cell (Courtemanche et al 1998)
  5. Cardiac Atrial Cell (Courtemanche et al 1998) (C++)
  6. Consequences of HERG mutations in the long QT syndrome (Clancy, Rudy 2001)
  7. Efffect of propofol on potassium current in cardiac H9c2 cells (Liu et al. 2008)
  8. FHF2KO and Wild-Type Mouse Cardiomyocyte Strands (Park et al 2020)
  9. Hysteresis in voltage gating of HCN channels (Elinder et al 2006, Mannikko et al 2005)
  10. INa and IKv4.3 heterogeneity in canine LV myocytes (Flaim et al 2006)
  11. Ionic basis of alternans and Timothy Syndrome (Fox et al. 2002), (Zhu and Clancy 2007)
  12. Kv4.3, Kv1.4 encoded K channel in heart cells & tachy. (Winslow et al 1999, Greenstein et al 2000)
  13. Kv4.3, Kv1.4 encoded K(+) channel in heart cells (Greenstein et al 2000) (XPP)
  14. Markovian model for cardiac sodium channel (Clancy, Rudy 2002)
  15. Markovian model for single-channel recordings of Ik_1 in ventricular cells (Matsuoka et al 2003)
  16. Model of arrhythmias in a cardiac cells network (Casaleggio et al. 2014)
  17. Role of KCNQ1 and IKs in cardiac repolarization (Silva, Rudy 2005)
  18. Role of KCNQ1 and IKs in cardiac repolarization (Silva, Rudy 2005) (XPP)
  19. Simulation study of Andersen-Tawil syndrome (Sung et al 2006)
  20. Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++)
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